Gaoligong tectonic belt is located in the eastern Gangdise block, and Gaoligong granites in the western Yunnan Province constitute an important magmatic record of Gangdise tectonic movement. Research on the geochemical characteristics of Puchuan granites in the southern Menglian granites of Gaoligong tectonic belt suggests that these granites with strong peraluminous character can be assigned to high-K calc-alkaline granites. Geochemical and chronological data of these granites are consistent to those of granites in northern and central Gaoligong tectonic belts. The formation of Puchuan granites might have been a magmatic response to collision of Nujiang tectonic belt in the western Yunnan Province.