The altitude in Qaidam Basin has getting higher since Cenozoic because the basin has been in the structure setting of the Tibetan Plateau continuous and periodical uplifting, which makes the basin have a close, dry and cold environment and abundant salt source. So the key point of hydrocarbon accumulation is the carrying capacity of fracture-sand conducting system. It is obvious that slope break belts controlling the sandbodies and hydrocarbon accumulation along the fractures in plateau saline lake basin. In summary, the favorable areas for lithologic reservoir are below the slope break belts with rich conducting fractures.