Nd isotope of ocean waters has become an important tracer for continental weathering and oceanic circulation. Dissolved oceanic Nd is controlled by input from continental weathering, while hydrothermal input can be ignored. The Nd isotope composition of seawater is not uniform in the present-day oceans because the oceanic residence time (500~1 000 a) of Nd is shorter than the mixing time (~1500 a) of the ocean and the relative contributions of Nd from ancient continental versus young volcanogenic materials differ in various basins. Therefore, the Nd isotope system has been used as a tracer for water exchange and paleo-ocean circulation. The combination of Nd isotope and the proxies for climate change can be used to study the relationship between ocean circulation and climate shifts. Nd isotope of surface water can provide information about continental weathering input.