Turning towards the geological complex conditions of coalbed methane (CBM) in Panxian, western Guizhou Province, the tectonic control of the CBM reservoir was discussed taking the tectonic evolution as a basic approach and combining with the geological field observation and the lab analysis. The results showed that four tectonic stages in the area have be experienced including the intra-continental rift stage from Devonian to Permian, stable platform stage from Early to Middle Triassic, continental depression stage from Late Triassic to Middle Jurassic and fault-folded uplift stage form Late Jurassic to Quaternary. Coal seams occur in the synclines indicating an obvious syncline control of CBM resources.