The Mufushan granite is outcropping at Taolin Pb-Zn deposit which is located in Qinzhou-Hangzhou metallogenic belt. The main body of granite is biotite monzogranite. In Geochemistry, the granite has the similarity with the C-type adakitic rocks of eastern China. It was obvious that the granite is enriched in LREE and LILE, and depleted in HREE and HFSE. It has right-dip chondrite-normalized REE pattern and flat HREE distribution. The ore-forming elements are rich in Mufushan granite. Taolin Pb-Zn deposit which was controlled by the Taolin-fault was the complex-sources hydrothermal filling deposits. The biotite monzogranite was one of the sources of ore-forming materials.