///Through combining hydrochemical method and geochemical modeling, this paper studied the water-rock reaction of groundwater in Jinta Basin, in order to Sustainable exploitation of groundwater. The study shows that the hydrochemical types of surface water in this area aren’t obvious, which are predominantly bicarbonate and sulfate. The simulated results show that there generally occur the precipitation of aragonite, calcite and dolomite, and the dissolution of anhydrite, gypsum and halite in groundwater from southwest to northeast in Jinta Basin. The calculation and simulation above show that the groundwater in Jinta basin is proper for irrigation, according to its physical and chemical characteristics.