Based on a study of regional metallogenic regularity, this paper summarizes the prospecting criteria for the southern metallogenic belt in the Mian-Lue-Ning triangle area as follows: 1) strata composed of Proterozoic basement metamorphic volcanic rocks and adjacent clastic rock and carbonate rocks; 2) well-developed NE-NNE trending faults; 3) areas where fractures are filled with intermediate-basic veins; and 4) geochemical anomaly areas of such elements as Au, Ag, Cu and Zn. The authors analyzed the metallogenic conditions of the study area and considered that the study area had favorable conditions in search for gold deposits related to fractures.