The analysis of fluid migration and rapid hydrocarbon accumulation is essential for exploring distribution of overpressure and probing into its generaion. Based on the RFT of many drills in Bozhong Depression, the characteristics and generation of reservoir overpressure have been discussed in this paper. Detailed investigation of reservoir overpressure in the Bozhong Depression shows that overpressure probably is the result of a combination of following three mechanisms: mechanical compaction disequilibrium, overpressure transference and thermal cracking.