This paper describes a success example for exploration of oil and gas field on the northern shoulder of the Dnieper-Donets Basin. The Dnieper-Donets Basin was a Late Devonian rifting basin, deposited post-rifting sediments from Carboniferous to Early Permian. In the first 45 year period of the geological study of the northern shoulder of the Dnieper-Donets Basin, its sedimentation, metamorphism and igneous rock had been condemned as possessing no potential for petroleum production for reasons of the complete absence of “source rock” and the presence of active, strongly-circulating artesian waters. The inspiration to exploration of oil and gas field in China is also discussed in this paper.