Large-scale thrust systems formed in Paleocene-Eocene in central Tibetan Plateau, e.g. Gangdese Thrust System (GTS),West Namco Thrust (WNT), Lunpola Thrust System (LTS), North Tanggula Thrust (NTS) and South Kunlun sinistral-slip thrust faults (SKF), and major thrust systems evidently controlled formation and evolution of Paleocene-Eocene basins. Regional magmatic plutonism and volcanic eruptions occurred in Gangdese areas in Paleocene-Early Eocene, and Sr/Y-Y geochemistry indicates that these magmatic rocks belong to island-arc magma caused by subduction of remained oceanic plate. Paleocene-Early Eocene subduction of remained oceanic plate transferred to subduction of India continental plate in 46~45 Ma.