The Abe silver lead-zinc deposit is situated in the South of the northern Altyn Tagh margin fault, its orebodies are mainly hosted in the partial brittle fault zone of Carboniferous monzogranite, orebody in Abei Silver Lead-zinc deposit occurs as veined, lenticular and zonary shapes along rimose and fractural zone. The composition of sulfur isotope probably suggested the sulfur in the ore fluid is the mixing of marine sediment source and magmatic source; the lead isotope showed the ore fluid is originated from upper crust. In conclusion, the Abe Silver Lead-zinc Deposit is a magmatic hydrothermal deposit that controlled by the fracture, mainly related to intermediate-acid magmatism.