上海市杨浦区退休与贫困妇女宫颈癌危险因素Logistic回归分析
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摘要
目的通过对上海市杨浦区退休与贫困妇女进行宫颈癌筛查,分析上海市杨浦区退休与贫困妇女宫颈癌的患病率,并在此基础上分析导致杨浦区退休与贫困妇女宫颈癌发病的相关危险因素,并提出针对性的预防措施。方法调查对象抽取自2013—2014年在杨浦区控江医院进行"二病"筛查的杨浦区退休与贫困妇女,所有调查结果经过专人核对后输入计算机,采用SPSS 12.0统计学软件包进行分析,单因素检验采用χ2检验,以P<0.05表示差异有统计学意义。单因素χ2检验有统计学意义的因素纳入多因素非条件Logistic回归法,从而分析得出导致上海市杨浦区退休与贫困妇女发生宫颈癌的相关危险因素。结果宫颈癌与HPV感染、经济条件及年龄有一定相关性,而怀孕次数、初次性交年龄、性伴侣数、肿瘤家族史、长期服避孕药及卫生条件六因素为促进宫颈癌发生的协同因素。结论宫颈癌的发生与多因素相关。
OBJECTIVE Through the screening of cervical cancer in Yangpu District retired and poor women in Shanghai City,analy-sis of the prevalence rate of cervical cancer among retired and poor women in Shanghai City Yangpu District; on the basis of which,the analysis lead to the risk of cervical cancer in Yangpu District women's retirement and poverty factors,and put forward specificprevention measures. METHODS The investigation object extractionfrom Yangpu District retired and poor women from 2013 to 2014 years of twodisease screening in Yangpu District Kongjiang Hospital,all the results of the survey after hand check input computer,the package was analyzed by SPSS 12.0 Statistical Software, the single factor test using chi square test, P<0.05. There is signifi-cant difference in. Single factors of chi square test with statistical significance into multiple factor non and analysis of related risk ofShanghai City Yangpu District retired and poor women cervical cancer factorconditional Logistic regression method. RESULTS Cervi-cal carcinoma with HPV infection,economic conditions,age had certain relevance,and the number of pregnancy,age of first sexu-al intercourse, number of sexual partners, family history of cancer, long-term oral contraceptives, healthconditions were the fac-tors for promoting cervical cancer. CONCLUSION The incidence of cervical cancer associated with multiple factors.
OBJECTIVE Through the screening of cervical cancer in Yangpu District retired and poor women in Shanghai City,analy-sis of the prevalence rate of cervical cancer among retired and poor women in Shanghai City Yangpu District; on the basis of which,the analysis lead to the risk of cervical cancer in Yangpu District women's retirement and poverty factors,and put forward specificprevention measures. METHODS The investigation object extractionfrom Yangpu District retired and poor women from 2013 to 2014 years of twodisease screening in Yangpu District Kongjiang Hospital,all the results of the survey after hand check input computer,the package was analyzed by SPSS 12.0 Statistical Software, the single factor test using chi square test, P<0.05. There is signifi-cant difference in. Single factors of chi square test with statistical significance into multiple factor non and analysis of related risk ofShanghai City Yangpu District retired and poor women cervical cancer factorconditional Logistic regression method. RESULTS Cervi-cal carcinoma with HPV infection,economic conditions,age had certain relevance,and the number of pregnancy,age of first sexu-al intercourse, number of sexual partners, family history of cancer, long-term oral contraceptives, healthconditions were the fac-tors for promoting cervical cancer. CONCLUSION The incidence of cervical cancer associated with multiple factors.
引文
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[9]Altekruse S F,Lacey J V,Brinton La,et al.Comparison of hu-man papillomavirus genotypes,sexual,and reproductive risk fac-tors of cervical adenocarcinoma and squamous cell carcinoma:Northeastern United States[J].Am J Obstet Gyneco1,2003,l88(3):657-663.
[10]Bosch F X,Munoz N,De Sanjose S,et al.Risk factors for cer-vical Cancer in Colombia and Spain[J].Int J cnacer,1992,52(5):750-758.
[11]李雅琪,龚勋,马燕,等.凉山州妇女宫颈癌危险因素的流行病学调查[J].现代肿瘤医学,2011,19(2):356-359.
[2]Basu B,Basu S,Chakraborti B,et.al.A comparison of dose dis-tribution from manchester-style and fletcher-style intracavitarybrachytherapy applicator systems in cervical cancer[J].J ContempBrachytherapy,2012,4(4):213-218.
[3]Lofters A K,Moineddin R,Hwang S W,et al.Does social disad-vantage affect the validity of self-report for cervical cancer screen-ing[J].Int J Womens Health,2013,5(2):29-33.
[4]Parkin D M,Bray F,Ferlay J,et a1.Global cancer statistics,2002[J].CA Cancer J Clin,2005,55(2):74-108.
[5]Parkin D M,Bray F,Ferlay J,et a1.Estimating the world cancerburden:Globocan 2000[J].Int J Cancer,2001,94(2):153-156.
[6]Velema J P,Ferrera A,Figueroa M,et al.Burning wood in thekitchen increase the risk of cervical neoplasia in HPV infectedwomen in Honduras[J].Int JCancer,2002,97(4):536-541.
[7]Perez L A.Genital HPV:links to cervical cancer,treatment,and prevention[J].Clin Lab Sci,2001,14(3):183-186.
[8]Green J,Berrington de Gonzalez A,Sweetland S,et al.Risk fac-tors for adenocarcinoma and squamous cell carcinoma of the cervixin women aged 20-44years:the UK National Case-Control Studyof Cervical Cancer[J].Br J Cancer,2003,89(11):2078-2086.
[9]Altekruse S F,Lacey J V,Brinton La,et al.Comparison of hu-man papillomavirus genotypes,sexual,and reproductive risk fac-tors of cervical adenocarcinoma and squamous cell carcinoma:Northeastern United States[J].Am J Obstet Gyneco1,2003,l88(3):657-663.
[10]Bosch F X,Munoz N,De Sanjose S,et al.Risk factors for cer-vical Cancer in Colombia and Spain[J].Int J cnacer,1992,52(5):750-758.
[11]李雅琪,龚勋,马燕,等.凉山州妇女宫颈癌危险因素的流行病学调查[J].现代肿瘤医学,2011,19(2):356-359.
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