High prevalence of genital HPV infection among long-term monogamous partners of women with cervical dysplasia or genital warts—Another reason for HPV vaccination of boys

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• 作者：Filip Rob ; Ruth Tachezy ; Tom&aacute ; š Pichlí ; k ; Luk&aacute ; š Rob ; Zuzana Kružicov&aacute ; Eva Hamší ; kov&aacute ; Jana Šmahelov&aacute ; and Jana Hercogov&aacute
• 刊名：Dermatologic Therapy
• 出版年：2017
• 出版时间：January/February 2017
• 年：2017
• 卷：30
• 期：1
• 全文大小：345K
• ISSN：1529-8019

文摘

We conducted a cross-sectional study on the occurrence of a specific type of genital human papillomavirus (HPV) among long-term monogamous male partners of women with cervical dysplasia and genital warts. The purpose of the study was to improve knowledge with regards to the management of these couples. The presence of genital HPV-DNA was detected by PCR with broad spectrum primers followed by hybridization. 82 males met the study criteria, 41 in each group. Genital HPV-DNA prevalence was 67.5% in the genital warts group and 72.2% in the cervical dysplasia group. The prevalence of high risk HPVs was higher in the cervical dysplasia group, while low risk HPVs were more prevalent in the genital warts group (p < .05). The prevalence of HPV in males was independent of the duration of the relationship (73.5% for 6–24 months and 66.7% for longer relationships). In conclusion, our results suggest that the prevalence of the genital HPV infection in both groups of male partners is comparable and very high, but the spectrum of HPV types varies significantly. The presence of the genital HPV infection in male sexual partners seems to be independent of the duration of the relationship. Applying the HPV vaccination to boys may prevent this phenomenon.