The expression of podoplanin is associated with poor outcome in cutaneous squamous cell carcinoma

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• 作者：Javier Cañ ; ueto ; Ester Cardeñ ; oso-&Aacute ; lvarez ; Adriana Cosano-Quero ; &Aacute ; ngel Santos-Briz ; Emilia Fern&aacute ; ndez-Ló ; pez ; Jesú ; s Pé ; rez-Losada and Concepció ; n Rom&aacute ; n-Curto
• 刊名：Journal of Cutaneous Pathology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：44
• 期：2
• 页码：144-151
• 全文大小：818K
• ISSN：1600-0560

文摘

Cutaneous squamous cell carcinoma (CSCC) is the second most frequent cancer in humans and can be both locally invasive and metastatic at distant sites. While research efforts have been made to predict poor outcome of CSCC, there is a lack of knowledge regarding molecular markers. Podoplanin has been associated with poor outcome in several types of cancer including CSCC, but this is controversial and only a few studies have evaluated the prognostic implications of podoplanin in the development of this tumor.