“Inherently Chiral” Ionic-Liquid Media: Effective Chiral Electroanalysis on Achiral Electrodes

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• 作者：Dr. Simona Rizzo ; Dr. Serena Arnaboldi ; Dr. Voichita Mihali ; Dr. Roberto Cirilli ; Dr. Alessandra Forni ; Prof. Armando Gennaro ; Prof. Abdirisak Ahmed Isse ; Prof. Marco Pierini ; Prof. Patrizia Romana Mussini and Prof. Francesco Sannicolò
• 刊名：Angewandte Chemie International Edition
• 出版年：2017
• 出版时间：February 13, 2017
• 年：2017
• 卷：56
• 期：8
• 页码：2079-2082
• 全文大小：1901K
• ISSN：1521-3773

文摘

To achieve enantioselective electroanalysis either chiral electrodes or chiral media are needed. High enantiodiscrimination properties can be granted by the “inherent chirality” strategy of developing molecular materials in which the stereogenic element responsible for chirality coincides with the molecular portion responsible for their specific properties, an approach recently yielding outstanding performances as electrode surfaces. Inherently chiral ionic liquids (ICILs) have now been prepared starting from atropisomeric 3,3′-bicollidine, synthesized from inexpensive reagents, resolved into antipodes without need of chiral HPLC and converted into long-chain dialkyl salts with melting points below room temperature. Both the new ICILs and shorter family terms, solid at room temperature, employed as low-concentration additives in achiral ILs, afford impressive enantioselection for the enantiomers of different probes on achiral electrodes, regularly increasing with additive concentration.