Recurrent and second primary squamous cell carcinoma of the head and neck: When and how to reirradiate
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- 作者：Primož Strojan ; June Corry ; Avraham Eisbruch ; Jan B. Vermorken ; William M. Mendenhall ; Anne W. M. Lee ; Missak Haigentz Jr ; Jonathan J. Beitler ; Remco de Bree ; Robert P. Takes ; Vinidh Paleri ; Charles G. Kelly ; Eric M. Genden ; Carol R. Bradford ; Louis B. Harrison ; Alessandra Rinaldo and Alfio Ferlito
- 关键词：head and neck cancer ; squamous cell carcinoma ; recurrence ; second primary cancer ; reirradiation ; salvage surgery ; systemic therapy
- 刊名：Head & Neck
- 出版年：2015
- 出版时间：January 2015
- 年：2015
- 卷：37
- 期：1
- 页码：134-150
- 全文大小：209K
- ISSN：1097-0347
文摘
Local and/or regional recurrence and metachronous primary tumor arising in a previously irradiated area are rather frequent events in patients with head and neck squamous cell carcinoma (HNSCC). Re-treatment is associated with an increased risk of serious toxicity and impaired quality of life (QOL) with an uncertain survival advantage.