Comparative B-mode and Doppler renal ultrasonography with histopathological findings in dogs positive for canine visceral leishmaniasis
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- 作者：Pollyana Irene Baltazar ; Laecio Da Silva Moura ; Gerson Tavares Pessoa ; Renan Paraguassu De Sá ; Rodrigues ; Marina Pinto Sanches ; Anaemilia Das Neves Diniz ; Francisco Das Chagas Araú ; jo Sousa ; Porfí ; rio Candanedo Guerra ; Willams Costa Neves ; Robson Fortes Giglio ; Jacyara De Jesus Rosa Pereira Alves ; Francisco De Assis Leite Souza ; Juliana Fortes Vilarinho Braga and Flá ; vio Ribeiro Alves
- 刊名：Microscopy Research and Technique
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：79
- 期：7
- 页码：637-645
- 全文大小：606K
- ISSN：1097-0029
文摘
Morphological parameters and renal flow were assessed and measured in six clinically healthy dogs with negative serological and parasitological examinations for canine visceral leishmaniasis (CVL) and six dogs with CVL-positive serological and parasitological tests and asymptomatic condition of the disease. Kidney length and diameter were measured and compared with the aorta/kidney ratio. Alterations in flow were measured using the flow velocity (cm/s) and resistance index (RI). Renal function was assessed by serum biochemical examination (urea, creatine, total proteins, albumin, and globulin) and urinalysis. CVL-positive animals presented heterogeneous kidney echotexture, reduced vascular flow, hypoperfusion, lesser visualization of the arcuate arteries, high RI values (1.06 ± 0.28 for the right kidney and 1.10 ± 0.30 for the left kidney), reduced diastolic flow, and high systolic peak. They also presented positive creatine/RI correlation and between the renal artery vascular flow and kidney diameter. Histopathological analysis of CVL-positive animals was compatible and confirmed hemodynamic changes observed by Doppler ultrasound. The findings in the present study showed that Doppler ultrasonography is a valid method to assess and detect alterations in flow in renal pathological processes with kidney vascular damage, as in the case of leishmaniasis, and can help in the diagnosis of animals with this infection. Microsc. Res. Tech. 79:637–645, 2016.