Immunohistochemical expression of cyclooxygenase-2 (COX-2) in oral nevi and melanoma

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• 作者：Juliana de Souza do Nascimento ; Romá ; n Carlos ; Wilson Delgado-Azañ ; ero ; Adalberto Mosqueda Taylor ; Oslei Paes de Almeida ; Má ; rio José ; Romañ ; ach and Bruno Augusto Benevenuto de Andrade
• 刊名：Journal of Oral Pathology & Medicine
• 出版年：2016
• 出版时间：July 2016
• 年：2016
• 卷：45
• 期：6
• 页码：440-443
• 全文大小：1033K
• ISSN：1600-0714

文摘

Cyclooxygenase-2 (COX-2) catalyses the conversion of arachidonic acid to prostaglandin, and its overexpression has been demonstrated in different malignant tumors, including cutaneous melanoma. However, no data about the expression of this protein in oral melanocytic lesions are available to date. The aim of this study was to evaluate the immunohistochemical expression of COX-2 in oral nevi and melanomas, comparing the results with correspondent cutaneous lesions.