Antiepileptic drugs, foetal malformations and spontaneous abortions

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• 作者：F. J. E. Vajda ; T. J. O'Brien ; J. E. Graham ; A. A. Hitchcock ; C. M. Lander and M. J. Eadie
• 刊名：Acta Neurologica Scandinavica
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：135
• 期：3
• 页码：360-365
• 全文大小：418K
• ISSN：1600-0404

文摘

Some recent studies have found an association between foetal malformations in earlier antiepileptic drug (AED)-exposed pregnancies and an increased hazard of such malformations in subsequent pregnancies. We investigated this matter further, and also considered the possible role of spontaneous abortions in previous pregnancies, in this situation.