Neuroanatomical variation in autism spectrum disorder: A comprehensive review

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• 作者：Fareed Jumah ; Malik Ghannam ; Mohammad Jaber ; Nimer Adeeb and R. Shane Tubbs
• 关键词：autism ; anatomical ; variations ; brain ; neuroanatomy
• 刊名：Clinical Anatomy
• 出版年：2016
• 出版时间：May 2016
• 年：2016
• 卷：29
• 期：4
• 页码：454-465
• 全文大小：144K
• ISSN：1098-2353

文摘

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by impairments in socialization, communication, and behavior. Many investigators have described the anatomical abnormalities in autistic brains, in an attempt to correlate them with the manifestations of ASD. Herein, we reviewed all the available literature about the neuroanatomical findings in ASD available via “PubMed” and “Google Scholar.” References found in review articles were also searched manually. There was substantial discrepancy throughout the literature regarding the reported presence and significance of neuroanatomical findings in ASD, and this is thoroughly discussed in the present review. Clin. Anat. 29:454–465, 2016.