Zinc Iodide-Mediated Direct Synthesis of 2,3-Dihydroisoxazoles from Alkynes and Nitrones

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• 作者：Zu-Feng Xiao ; Ting-Hui Ding ; Sheng-Wei Mao ; Xiao-Shan Ning and Yan-Biao Kang
• 刊名：Advanced Synthesis & Catalysis
• 出版年：2016
• 出版时间：June 2, 2016
• 年：2016
• 卷：358
• 期：11
• 页码：1859-1863
• 全文大小：534K
• ISSN：1615-4169

文摘

A zinc diiodide (ZnI₂)-mediated direct synthesis of 2,3-dihydroisoxazoles via a [3+2] cycloaddition reaction of the nitrones and non-electron-deficient terminal alkynes has been developed. This method was applied in the formal synthesis of HPA-12 and aminoglucose.