Efficacy of ranitidine in olanzapine-induced weight gain: a dose-response study

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• 作者：Varun S. Mehta and Daya Ram
• 刊名：Early Intervention in Psychiatry
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：10
• 期：6
• 页码：522-527
• 全文大小：546K
• ISSN：1751-7893

文摘

Weight gain has long been recognized as a side-effect of atypical antipsychotic drugs. Numerous new approaches have been tried for prevention of weight gain, the H2 blockers being one of them. The study was conducted with the aim to evaluate the efficacy of ranitidine in olanzapine-induced weight gain at two fixed doses of 150 and 300 mg day⁻¹.