Posterior tibial tendinopathy associated with matrix metalloproteinase 13 promoter genotype and haplotype
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- 作者：Francielle Boç ; on de Araujo Munhoz ; José ; Eduardo Baroneza ; Alexandre Godoy-Santos ; Tú ; lio Diniz Fernandes ; Filipe Polese Branco ; Lupe Furtado Alle ; Ricardo Lehtonen de Souza and Maria Cristina Leme Godoy dos Santos
- 刊名：The Journal of Gene Medicine
- 出版年：2016
- 出版时间：November-December 2016
- 年：2016
- 卷：18
- 期：11-12
- 页码：325-330
- 全文大小：158K
- ISSN：1521-2254
文摘
Posterior tibial tendon (PTT) is particularly vulnerable and its insufficiency is recognized as the main cause of adult acquired flat foot. Some patients have a predisposition without a clinically recognized cause, suggesting that individual characteristics play an important role in tendinopathy. The present study investigated whether genetic variants in matrix metalloproteinases (MMPs) are associated with PTT dysfunction.