ChemInform Abstract: Synthesis of Novel Dihydronaphthothiazine S,S-Dioxides by Intramolecular Sulfonylamidomethylation of 2-Naphthylmethanesulfonamides Using Amberlyst XN-1010.
The cyclization of sulfonamides (I) with s-trioxane proceeds with high regioselectivity toward C1 of the naphthalene ring, while cyclization of the 1-bromo derivative (IV) is directed toward C3.