Subsets of salivary duct carcinoma defined by morphologic evidence of pleomorphic adenoma, PLAG1 or HMGA2 rearrangements, and common genetic alterations
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- 作者：Simion I. Chiosea ; Lester D. R. Thompson ; Ilan Weinreb ; Julie E. Bauman ; Alyssa M. Mahaffey ; Caitlyn Miller ; Robert L. Ferris and William E. Gooding
- 刊名：Cancer
- 出版年：2016
- 出版时间：October 15, 2016
- 年：2016
- 卷：122
- 期：20
- 页码：3136-3144
- 全文大小：433K
- ISSN：1097-0142
文摘
The authors hypothesized that histogenetic classification of salivary duct carcinoma (SDC) could account for de novo tumors and those with morphologic or molecular evidence (pleomorphic adenoma gene 1 [PLAG1], high-mobility group AT hook 2 [HMGA2] rearrangement, amplification) of pleomorphic adenoma (PA).