Causes of Elevated Cardiac Troponins in the Emergency Department and Their Associated Mortality

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• 作者：Stephen Meigher ; Henry C. Thode ; W. Frank Peacock ; Jay L. Bock ; Louis Gruberg and Adam J. Singer
• 刊名：Academic Emergency Medicine
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：23
• 期：11
• 页码：1267-1273
• 全文大小：279K
• ISSN：1553-2712

文摘

Cardiac troponins (cTn) are structural components of myocardial cells and are expressed almost exclusively in the heart. Elevated cTn levels indicate myocardial cell damage/death but not reflect the underlying etiology. The third universal definition of myocardial infarction (MI) differentiates MI into various types. Type 1 (T1MI) is due to plaque rupture with thrombus, while type 2 (T2MI) is a result of a supply:demand mismatch. Non-MI cTn elevations are also common. We determined the causes of elevated cTn in a tertiary care emergency department (ED) and the associated in-hospital mortality.