Analysis of Complete Remission in Systemic Lupus Erythematosus Patients Over a 32-Year Period

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• 作者：Carmen V. Medina-Quiñ ; ones ; Luc&#237 ; a Ramos-Merino ; Pablo Ruiz-Sada and David Isenberg
• 刊名：Arthritis Care & Research
• 出版年：2016
• 出版时间：July 2016
• 年：2016
• 卷：68
• 期：7
• 页码：981-987
• 全文大小：204K
• ISSN：2151-4658

文摘

Systemic lupus erythematosus (SLE) is characterized by an unpredictable and fluctuating course. Although various methods have been developed to measure disease activity, there is still a lack of consensus about the optimal criteria for SLE remission. The principal aim of our study was to identify the number of lupus patients achieving a complete remission (implying that for 3 years there were no clinical or serologic features and no treatment with steroids and immunosuppressive drugs) in a single cohort of patients followed for a period of up to 32 years. In addition, we have identified patients in clinical but not serologic remission (known as serologically active, clinically quiescent disease [SACQ]) and vice versa. We were particularly interested to determine the factors associated with complete remission.