Brain structural changes in patients with chronic myofascial pain

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• 作者：D.M. Niddam ; S.-H. Lee ; Y.-T. Su and R.-C. Chan
• 刊名：European Journal of Pain
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：21
• 期：1
• 页码：148-158
• 全文大小：376K
• ISSN：1532-2149

文摘

Myofascial trigger points (MTrPs) are a highly prevalent source of musculoskeletal pain. Prolonged ongoing nociceptive input from MTrPs may lead to maladaptive changes in the central nervous system. It remains, however, unknown whether pain from MTrPs is associated with brain atrophy. In addition, stress, which may contribute to the formation of MTrPs, is also known to affect brain structures. Here, we address whether structural brain changes occur in patients with chronic pain originating from MTrPs and whether such changes are related to pain or stress.