Aliskiren directly improves endothelial progenitor cell function from Type II diabetic patients

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• 作者：Ting-Ting Chang ; Tao-Cheng Wu ; Po-Hsun Huang ; Jia-Shiong Chen ; Liang-Yu Lin ; Shing-Jong Lin and Jaw-Wen Chen
• 刊名：European Journal of Clinical Investigation
• 出版年：2016
• 出版时间：June 2016
• 年：2016
• 卷：46
• 期：6
• 页码：544-554
• 全文大小：501K
• ISSN：1365-2362

文摘

Endothelial progenitor cell (EPC) functions are impaired in the presence of diabetes mellitus. Aliskiren is a direct renin inhibitor, which is expected to modify proangiogenic cells. This study aimed to investigate whether and how aliskiren could improve the function of EPCs from patients with type II diabetes (T2DM).