Too good to treat? ischemic stroke patients with small computed tomography perfusion lesions may not benefit from thrombolysis

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• 作者：Andrew Bivard ; Min Lou ; Christopher R. Levi ; Venkatesh Krishnamurthy ; Xin Cheng ; Richard I. Aviv ; Patrick McElduff ; Longting Lin ; Tim Kleinig ; Billy O' ; Brien ; Kenneth Butcher ; Zhang Jingfen ; Jim Jannes ; Qiang Dong and Mark W. Parsons
• 刊名：Annals of Neurology
• 出版年：2016
• 出版时间：August 2016
• 年：2016
• 卷：80
• 期：2
• 页码：286-293
• 全文大小：358K
• ISSN：1531-8249

文摘

Although commonly used in clinical practice, there remains much uncertainty about whether perfusion computed tomography (CTP) should be used to select stroke patients for acute reperfusion therapy. In this study, we tested the hypothesis that a small acute perfusion lesion predicts good clinical outcome regardless of thrombolysis administration.