ChemInform Abstract: Metal-Free Tandem Oxidative C(sp3)—H Bond Functionalization of Alkanes and Dearomatization of N-Phenyl-cinnamamides: Access to Alkylated 1-Azaspiro[4.5]decanes.
The title reaction provides a direct method for the synthesis of alkylated 1-azaspiro[4.5]decanes with excellent regioselectivity and diastereoselectivity.