Towards Uniform Iodine Catalysis: Intramolecular C−H Amination of Arenes under Visible Light
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- 作者：Dr. Claudio Martí ; nez ; Alexandra E. Bosnidou ; Dr. Simon Allmendinger and Prof. Dr. Kilian Muñ ; iz
- 刊名：Chemistry - A European Journal
- 出版年：2016
- 出版时间：July 11, 2016
- 年：2016
- 卷：22
- 期：29
- 页码：9929-9932
- 全文大小：967K
- ISSN：1521-3765
文摘
A photochemical catalytic amination of arenes is presented. The reaction proceeds under benign iodine catalysis in the presence of visible light as the initiator and provides access to a range of differently substituted arylamines. A total of 29 examples demonstrate the broad applicability of this mild oxidation method. The scope of the reaction could further be expanded to silyl-tethered derivatives, which undergo intramolecular amination upon formation of seven-membered heterocycles. Cleavage of the silicon tether provides access to the corresponding 3-substituted anilines.