Computational meta-analysis of statistical parametric maps in major depression

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• 作者：Danilo Arnone ; Dominic Job ; Sudhakar Selvaraj ; Osamu Abe ; Francesco Amico ; Yuqi Cheng ; Sean J. Colloby ; John T. O' ; Brien ; Thomas Frodl ; Ian H. Gotlib ; Byung-Joo Ham ; M Justin Kim ; P Cé ; dric MP Koolschijn ; Cintia A.-M. Pé ; rico ; Giacomo Salvadore ; Alan J. Thomas ; Marie-José ; Van Tol ; Nic J.A. van der Wee ; Dick J. Veltman ; Gerd Wagner and Andrew M. McIntosh
• 关键词：magnetic resonance imaging ; depression ; affective disorders ; meta-analysis
• 刊名：Human Brain Mapping
• 出版年：2016
• 出版时间：April 2016
• 年：2016
• 卷：37
• 期：4
• 页码：1393-1404
• 全文大小：354K
• ISSN：1097-0193

文摘

Several neuroimaging meta-analyses have summarized structural brain changes in major depression using coordinate-based methods. These methods might be biased toward brain regions where significant differences were found in the original studies. In this study, a novel voxel-based technique is implemented that estimates and meta-analyses between-group differences in grey matter from individual MRI studies, which are then applied to the study of major depression.