Toxicity and dosimetric analysis of non-small cell lung cancer patients undergoing radiotherapy with 4DCT and image-guided intensity modulated radiotherapy: a regional centre's experience
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- 作者：Gareth C. Livingston ; Andrew J. Last ; Thomas P. Shakespeare ; Patrick M. Dwyer ; Justin Westhuyzen ; Michael J. McKay ; Lisa Connors ; Stephanie Leader and Stuart Greenham
- 刊名：Journal of Medical Radiation Sciences
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：63
- 期：3
- 页码：170-178
- 全文大小：369K
- ISSN：2051-3909
文摘
For patients receiving radiotherapy for locally advance non–small cell lung cancer (NSCLC), the probability of experiencing severe radiation pneumonitis (RP) appears to rise with an increase in radiation received by the lungs. Intensity modulated radiotherapy (IMRT) provides the ability to reduce planned doses to healthy organs at risk (OAR) and can potentially reduce treatment-related side effects. This study reports toxicity outcomes and provides a dosimetric comparison with three-dimensional conformal radiotherapy (3DCRT).