Cancer-specific promoters for expression-targeted gene therapy: ran, brms1 and mcm5

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• 作者：Xuguang Chen ; Jacqueline E. Scapa ; David X. Liu and W T. Godbey
• 刊名：The Journal of Gene Medicine
• 出版年：2016
• 出版时间：July 2016
• 年：2016
• 卷：18
• 期：7
• 页码：89-101
• 全文大小：433K
• ISSN：1521-2254

文摘

To expand the library of promoters that can be used for expression-targeted gene delivery to cancer cells, the specificity and strength of expression of three cancer-related gene promoters was evaluated: RAS-related nuclear protein (<sup>Psup>ran), breast cancer metastasis suppressor 1 (<sup>Psup>brms1) and minichromosome maintenance complex component 5 (<sup>Psup>mcm5).