A case of gabapentin-induced rhabdomyolysis requiring renal replacement therapy

详细信息    查看全文

• 作者：Min Seok Choi ; Howook Jeon ; Hyo Suk Kim ; Bo Hyun Jang ; Yoon Hee Lee ; Hoon Suk Park ; HyungWook Kim and Dong Chan Jin
• 刊名：Hemodialysis International
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：21
• 期：1
• 页码：E4-E8
• 全文大小：182K
• ISSN：1542-4758

文摘

Gabapentin is commonly used for controlling convulsions, restless pain syndrome, and pain in diabetic neuropathy. Common side effects include dizziness, somnolence, ataxia, peripheral edema, and confusion; gabapentin-induced rhabdomyolysis is rarely reported. To date, the reported cases of gabapentin-induced rhabdomyolysis have been associated with patients with multiple underlying diseases and assuming multiple medicines for various reasons. In this report, we describe a case of gabapentin-induced rhabdomyolysis in a 32-year-old woman with no medical history. We also review related literature and discuss the possible mechanism and the association with other factors. This case shows that gabapentin can induce rhabdomyolysis in healthy patients and that clinicians must consider the possible association between gabapentin and rhabdomyolysis.