Cortical sensorimotor alterations classify clinical phenotype and putative genotype of spasmodic dysphonia

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• 作者：G. Battistella ; S. Fuertinger ; L. Fleysher ; L. J. Ozelius and K. Simonyan
• 刊名：European Journal of Neurology
• 出版年：2016
• 出版时间：October 2016
• 年：2016
• 卷：23
• 期：10
• 页码：1517-1527
• 全文大小：645K
• ISSN：1468-1331

文摘

Spasmodic dysphonia (SD), or laryngeal dystonia, is a task-specific isolated focal dystonia of unknown causes and pathophysiology. Although functional and structural abnormalities have been described in this disorder, the influence of its different clinical phenotypes and genotypes remains scant, making it difficult to explain SD pathophysiology and to identify potential biomarkers.