Inside Cover: Phosphite-Thiother Ligands Derived from Carbohydrates allow the Enantioswitchable Hydrogenation of Cyclic β-Enamides by using either Rh or Ir Catalysts (Chem. Eur. J. 4/2017)
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- 作者：Dr. Jè ; ssica Margalef ; Dr. Oscar Pà ; mies and Prof. Montserrat Dié ; guez
- 刊名：Chemistry - A European Journal
- 出版年：2017
- 出版时间：January 18, 2017
- 年：2017
- 卷：23
- 期：4
- 页码：723
- 全文大小：2136K
- ISSN：1521-3765
文摘
Both enantiomers of 2-aminotetralines and 3-aminochromanes are easily accessible via asymmetric hydrogenation by simply switching from Rh to Ir. The chiral information is provided by a phosphite-thioether ligand, with a simple architecture, derived from d-mannitol. This picture illustrates how the chiral pool can be used to synthesize these phosphite-thioether ligands that in combination with either Rh- or Ir-catalyst precursors allow the efficient enantioswitchable hydrogenation of cyclic β-enamides. More information can be found in the Full Paper by O. Pàmies and M. Diéguez et al. on page 813 ff.