A Mitochondrion-Specific Photoactivatable Fluorescence Turn-On AIE-Based Bioprobe for Localization Super-Resolution Microscope
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- 作者：Xinggui Gu ; Engui Zhao ; Teng Zhao ; Miaomiao Kang ; Chen Gui ; Jacky W. Y. Lam ; Shengwang Du ; Michael M. T. Loy and Ben Zhong Tang
- 刊名：Advanced Materials
- 出版年：2016
- 出版时间：July 6, 2016
- 年：2016
- 卷：28
- 期：25
- 页码：5064-5071
- 全文大小：1739K
- ISSN：1521-4095
文摘
A novel mitochondrion-specific photoactivatable fluorescence turn-on bioprobe, named as o-TPE-ON+, is designed and readily prepared, operating through a new photoactivatable mechanism of photocyclodehydrogenation. This bioprobe exhibits unique photoactivation behavior in cells, and is applied to super-resolution imaging of mitochondrion and its dynamic investigation in both fixed and live cells under physiological conditions without any external additives.