Ruthenium(II)-Catalyzed Oxidant-Free C-H Olefination of Aromatic Carboxamides with Allyl Acetate

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• 作者：Feifei Li ; Cong Shen ; Jian Zhang ; Ling Wu ; Xupeng Zhuo ; Liyuan Ding and Guofu Zhong
• 刊名：Advanced Synthesis & Catalysis
• 出版年：2016
• 出版时间：December 22, 2016
• 年：2016
• 卷：358
• 期：24
• 页码：3932-3937
• 全文大小：1078K
• ISSN：1615-4169

文摘

An inexpensive ruthenium-catalyzed direct C–H olefination of aromatic carboxamides with allyl acetate was developed. This external oxidant-free protocol provided an efficient route for the synthesis of useful trans-styrene derivatives in high to excellent yields. The olefination reaction exhibited excellent regioselectivities and allowed the presence of a wide range of functional groups, such as OMe, F, Cl, Br, I, CF₃, NMe₂, as well as NO₂.