The impact of EndoBarrier gastrointestinal liner in obese patients with normal glucose tolerance and in patients with type 2 diabetes
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- 作者：Ulrich Rohde ; Cecilie A. Federspiel ; Peter Vilmann ; Ebbe Langholz ; Steffen U. Friis ; Martin Krakauer ; Jens F. Rehfeld ; Jens J. Holst ; Tina Vilsbø ; ll and Filip K. Knop
- 刊名：Diabetes, Obesity and Metabolism
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：19
- 期：2
- 页码：189-199
- 全文大小：874K
- ISSN：1463-1326
文摘
The duodenal-jejunal bypass sleeve ((DJBS) or EndoBarrier Gastrointestinal Liner) induces weight loss in obese subjects and may improve glucose homeostasis in patients with type 2 diabetes (T2D). To explore the underlying mechanisms, we evaluated postprandial physiology including glucose metabolism, gut hormone secretion, gallbladder emptying, appetite and food intake in patients undergoing DJBS treatment.