Bioinspired Total Syntheses of Isospongian-type Diterpenoids (−)-Kravanhins A and C
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- 作者：Zhuliang Zhong ; Gaoyuan Zhao ; Dengyu Xu ; Baobiao Dong ; Dengpeng Song ; Dr. Xingang Xie and Prof. Dr. Xuegong She
- 刊名：Chemistry – An Asian Journal
- 出版年：2016
- 出版时间：May 20, 2016
- 年：2016
- 卷：11
- 期：10
- 页码：1542-1547
- 全文大小：588K
- ISSN：1861-471X
文摘
The first bioinspired total syntheses of (−) kravanhins A and C were accomplished from a labdane diterpenoid derivative. The key reactions involve a photooxidation and a one-pot sequential aldol cyclization and lactonization, which provide a new plausible biosynthetic pathway for the kravanhins and other symbiotic members.