ChemInform Abstract: 1,1,1,3,3,3-Hexafluoroisopropanol as a Remarkable Medium for Atroposelective Sulfoxide-Directed Fujiwara—Moritani Reaction with Acrylates and Styrenes.
Access to atropo-enantioenriched chiral biaryl moieties through asymmetric direct C—H activation is achieved using an enantiopure sulfoxide as both the directing group and chiral auxiliary.