In Vitro Gene Delivery with Large Porous Silicon Nanoparticles Fabricated Using Cost-Effective, Metal-Assisted Chemical Etching
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- 作者：Nancy Wareing ; Kyle Szymanski ; Giridhar R. Akkaraju ; Armando Loni ; Leigh T. Canham ; Roberto Gonzalez-Rodriguez and Jeffery L. Coffer
- 刊名：Small
- 出版年：2017
- 出版时间：January 18, 2017
- 年：2017
- 卷：13
- 期：3
- 全文大小：811K
- ISSN：1613-6829
文摘
The cytocompatibility, cell membrane affinity, and plasmid DNA delivery from surface oxidized, metal-assisted stain-etched mesoporous silicon nanoscale particles (pSiNPs) to human embryonic kidney (HEK293) cells is demonstrated, suggesting the possibility of using such material for targeted transfection and drug delivery.