Evaluation of Malassezia and Common Fungal Pathogens in Subtypes of Chronic Rhinosinusitis

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• 作者：Jonathan T. Gelber ; Emily K. Cope ; Andrew N. Goldberg and Steven D. Pletcher
• 刊名：International Forum of Allergy & Rhinology
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：6
• 期：9
• 页码：950-955
• 全文大小：196K
• ISSN：2042-6984

文摘

Fungal hypersensitivity and fungal microbiome dysbiosis are possible etiologies of chronic rhinosinusitis. The sinus fungal microbiome is not well characterized; novel sinus-associated fungi, including Malassezia, have only recently been described. The goals for this study were to verify Malassezia as a dominant component of the sinus microbiome, to speciate sinus Malassezia, and to compare select fungal species in chronic rhinosinusitis (CRS) subtypes with known fungal association to chronic rhinosinusitis with polyps (CRSwNP) and healthy controls.