Mother's smoking and complex lung function of offspring in middle age: A cohort study from childhood

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• 作者：Jennifer L. Perret ; Haydn Walters ; David Johns ; Lyle Gurrin ; John Burgess ; Adrian Lowe ; Bruce Thompson ; James Markos ; Stephen Morrison ; Paul Thomas ; Christine McDonald ; Richard Wood-Baker ; John Hopper ; Cecilie Svanes ; Graham Giles ; Michael Abramson ; Melanie Matheson and Shyamali Dharmage
• 刊名：Respirology
• 出版年：2016
• 出版时间：July 2016
• 年：2016
• 卷：21
• 期：5
• 页码：911-919
• 全文大小：786K
• ISSN：1440-1843

文摘

Existing evidence that supports maternal smoking to be a potential risk factor for chronic obstructive pulmonary disease (COPD) for adult offspring has barely been mentioned in major guideline documents, suggesting a need for more robust and consistent data. We aimed to examine whether such early life exposure can predispose to COPD in middle age, possibly through its interaction with personal smoking.