14-3-3epsilon controls multiple developmental processes in the mouse heart
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- 作者：Adriana C. Gittenberger-de Groot ; Tamara Hoppenbrouwers ; Lucile Miquerol ; Yasuhiro Kosaka ; Robert E. Poelmann ; Lambertus J. Wisse ; H. Joseph Yost ; Monique R.M. Jongbloed ; Marco C. Deruiter and Luca Brunelli
- 刊名：Developmental Dynamics
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：245
- 期：11
- 页码：1107-1123
- 全文大小：3457K
- ISSN：1097-0177
文摘
14-3-3ε plays an important role in the maturation of the compact ventricular myocardium by modulating the cardiomyocyte cell cycle via p27kip1. However, additional cardiac defects are possible given the ubiquitous expression pattern of this protein.