Biomimicking Nano-Micro Binary Polymer Brushes for Smart Cell Orientation and Adhesion Control

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• 作者：Lina Chen ; Zhuang Xie ; Tiansheng Gan ; Yi Wang ; Guangzhao Zhang ; Chad A. Mirkin and Zijian Zheng
• 刊名：Small
• 出版年：2016
• 出版时间：July 6, 2016
• 年：2016
• 卷：12
• 期：25
• 页码：3400-3406
• 全文大小：2666K
• ISSN：1613-6829

文摘

A new biomimetic surface named nano-micro binary polymer brushes is fabricated by large-area bench-top dip-pen nanodisplacement lithography technique. It is composed of gelatin-modified poly(glycidyl methacrylate) nanolines which are spaced by microstripes of poly(N-isopropylacrylamide). Cells are not only adhered and oriented well on the re-used surface, but also detachable from the surface with well-preserved extracellular matrix and aligned morphology.