ChemInform Abstract: Kinetic Resolution of β-Sulfonyl Ketones Through Enantioselective β-Elimination Using a Cation-Binding Polyether Catalyst.

详细信息    查看全文

• 作者：Liang Li ; Yidong Liu ; Yang Peng ; Lei Yu ; Xiaoyan Wu and Hailong Yan
• 关键词：stereochemistry (general ; optical resolution) ; diastereoselective syntheses ; enantioselective syntheses (incl. cis/trans-isomerism) ; sulfoxides ; sulfones ; sulfenes and derivatives (benzene compounds)
• 刊名：ChemInform
• 出版年：2016
• 出版时间：April, 2016
• 年：2016
• 卷：47
• 期：19
• 全文大小：34K
• ISSN：1522-2667

文摘

In the presence of KF as reagent and a chiral BINOL-derived cation-binding polyether as catalyst, the first asymmetric β-elimination of sulfones of type (I) and (III) is achieved resulting in a kinetic resolution to give the corresponding (R)-sulfones with e.e.′s better than 90%.