Drug Therapy: An Amphiphilic Ruthenium Polymetallodrug for Combined Photodynamic Therapy and Photochemotherapy In Vivo (Adv. Mater. 6/2017)
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- 作者：Wen Sun ; Shuyi Li ; Bernhard Hä ; upler ; Juan Liu ; Shubin Jin ; Werner Steffen ; Ulrich S. Schubert ; Hans-Jü ; rgen Butt ; Xing-Jie Liang and Si Wu
- 刊名：Advanced Materials
- 出版年：2017
- 出版时间：February 10, 2017
- 年：2017
- 卷：29
- 期：6
- 全文大小：3499K
- ISSN：1521-4095
文摘
X.-J. Liang, S. Wu, and co-workers demonstrate a redlight-responsive Ru-containing block copolymer as a polymetallodrug for phototherapy in article 1603702. This block copolymer self-assembles into nanoparticles that can accumulate at the tumor sitet. Red-light irradiation induces release of the anticancer Ru complexes and generates cytotoxic 1O2, both of which inhibit the growth of cancer cell.